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Ultimate Guide About Benadryl Dosage For Dogs

Benadryl dosage for dogs

Allergic reactions can be scary, creepy and quick. Raised, puffy, swollen, inflamed and circular areas can show up in a blink. You may be fright to death to see these unexpected problems with your dog. If your dog has a history of allergies like chronic or acute then treating it with over the counter medicine like Benadryl is not recommended and you need to consult your vet to get rid of it but if your dog has developed itching due to any slightest irritant then Benadryl can be used as it is considered to be safe for dogs. So today we’ve decided to share with in-depth insights about Benadryl dosage for dogs that will help a great deal.

What is Benadryl?

Benadryl which is the trade name of Diphenhydramine is antihistamine and antiemetic mainly used to treat allergies, itchiness, common cold, insomnia, nausea, motion sickness, and extrapyramidal symptoms. Diphenhydramine which is an active ingredient of Benadryl actually works by reversing the effects of histamine (a naturally occurring substance present in the body) on the capillaries which as a result reduces the intensity of allergic symptoms.

Is Benadryl safe for dogs?

Diphenhydramine can be used safely for dogs, cats, and other pets. It is one of the most common over the counter drug which is used for a number of reasons like allergic respiratory disease, cough, pruritus, itching, allergic reactions to insect bites, bee stings, runny nose and eyes, squeezing, motion sickness, mild sedation and vaccination reactions but usually administering it to your dog for allergies is not recommended.

Although you can give Benadryl to your dog but it is not the ideal option as is specifically formulated keeping the human system in mind, it would be better if you opt for a drug specially formulated for canines like Apoquel.

Benadryl is not considered safe for dogs with elevated blood pressure, cardiovascular disease, and glaucoma. Similarly, giving puppy Benadryl is also not much safe, so consulting a vet is important.

Benadryl dosage in dogs

The amount of dosage is very crucial and will depend upon the size of the dog and should be administered very accurately as over dosage of Benadryl can cause some serious problems. The average dosage for oral Benadryl is 1 mg for per pound of dog, given 2-3 times a day. Most drug store diphenhydramine tablets are 25 mg, which is used to treat a 25 pound dog. Also, check the Benadryl tablets you give to your dog only contains the ingredient diphenhydramine as many formulations contain some other ingredients like acetaminophen or alcohol that are toxic for dogs.

You can treat your dog’s allergies with medication but it is always good to sort out the allergens and try to reduce them as much as possible. Some of the most simple things you can do at home to treat allergies are by feeding less allergic food including probiotics, regular bathing especially washing your dog’s feet when he/she comes from outside, chamomile tea spray to treat allergies safely.

We are sharing a Benadryl dosage chart for Dogs along with your dog’s weight to help you administer proper amount of drug to your dog.

Dog’s Weight

     (In lbs.)

Dog’s Weight

     (In kg)



5 lbs. 2.26 kg 5 mg
10 lbs. 4.53 kg 10 mg
20 lbs. 9.07 kg 20 mg
30 lbs. 13.60 kg 30 mg
40 lbs. 18.14 kg 40 mg
50 lbs. 22.67 kg 50 mg
60 lbs. 27.21 kg 60 mg
80 lbs. 36.28 kg 80 mg
100 lbs. 45.35 kg 90 mg
125 lbs. 56.69 kg 125 mg
150 lbs. 68.03 kg 150 mg

Possible side effects of Benadryl

Although considered safe for canines Benadryl too has some side effects. If you see any of these symptoms consult your vet immediately. These are:

  • Drowsiness
  • Dry mouth
  • Urinary retention
  • Vomiting
  • Diarrhea
  • Seizures
  • Extreme drowsiness
  • Coma
  • Respiratory depression

Can I give my dog Benadryl?

Yes, Benadryl is one of the medications that is considered quite safe for dogs unless your dog is suffering any underlying health issues. If your dog has glaucoma, high blood pressure, the cardiovascular disease then always contact your veterinarian before administering Benadryl to your dog as it is contraindicated with these conditions. Also, bring to your vet notice if your dog is pregnant or lactating. Always seek medical consultation before giving any medication to your dog for the life-long health and happiness of your companion.


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